Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke...
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doaj-c90ca4e0829d4065af60a33fe1bd2f2b2020-11-24T21:35:37ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017353810.1371/journal.pone.0173538Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.Roh-Eul YooTae Jin YunByung-Woo YoonSang Kun LeeSoon-Tae LeeKoung Mi KangSeung Hong ChoiJi-Hoon KimChul-Ho SohnSun-Won ParkMoon Hee HanThis study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures.http://europepmc.org/articles/PMC5349669?pdf=render |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Roh-Eul Yoo Tae Jin Yun Byung-Woo Yoon Sang Kun Lee Soon-Tae Lee Koung Mi Kang Seung Hong Choi Ji-Hoon Kim Chul-Ho Sohn Sun-Won Park Moon Hee Han |
spellingShingle |
Roh-Eul Yoo Tae Jin Yun Byung-Woo Yoon Sang Kun Lee Soon-Tae Lee Koung Mi Kang Seung Hong Choi Ji-Hoon Kim Chul-Ho Sohn Sun-Won Park Moon Hee Han Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. PLoS ONE |
author_facet |
Roh-Eul Yoo Tae Jin Yun Byung-Woo Yoon Sang Kun Lee Soon-Tae Lee Koung Mi Kang Seung Hong Choi Ji-Hoon Kim Chul-Ho Sohn Sun-Won Park Moon Hee Han |
author_sort |
Roh-Eul Yoo |
title |
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
title_short |
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
title_full |
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
title_fullStr |
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
title_full_unstemmed |
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
title_sort |
identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2017-01-01 |
description |
This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures. |
url |
http://europepmc.org/articles/PMC5349669?pdf=render |
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