Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.

This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke...

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Main Authors: Roh-Eul Yoo, Tae Jin Yun, Byung-Woo Yoon, Sang Kun Lee, Soon-Tae Lee, Koung Mi Kang, Seung Hong Choi, Ji-Hoon Kim, Chul-Ho Sohn, Sun-Won Park, Moon Hee Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5349669?pdf=render
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spelling doaj-c90ca4e0829d4065af60a33fe1bd2f2b2020-11-24T21:35:37ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017353810.1371/journal.pone.0173538Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.Roh-Eul YooTae Jin YunByung-Woo YoonSang Kun LeeSoon-Tae LeeKoung Mi KangSeung Hong ChoiJi-Hoon KimChul-Ho SohnSun-Won ParkMoon Hee HanThis study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures.http://europepmc.org/articles/PMC5349669?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Roh-Eul Yoo
Tae Jin Yun
Byung-Woo Yoon
Sang Kun Lee
Soon-Tae Lee
Koung Mi Kang
Seung Hong Choi
Ji-Hoon Kim
Chul-Ho Sohn
Sun-Won Park
Moon Hee Han
spellingShingle Roh-Eul Yoo
Tae Jin Yun
Byung-Woo Yoon
Sang Kun Lee
Soon-Tae Lee
Koung Mi Kang
Seung Hong Choi
Ji-Hoon Kim
Chul-Ho Sohn
Sun-Won Park
Moon Hee Han
Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
PLoS ONE
author_facet Roh-Eul Yoo
Tae Jin Yun
Byung-Woo Yoon
Sang Kun Lee
Soon-Tae Lee
Koung Mi Kang
Seung Hong Choi
Ji-Hoon Kim
Chul-Ho Sohn
Sun-Won Park
Moon Hee Han
author_sort Roh-Eul Yoo
title Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
title_short Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
title_full Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
title_fullStr Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
title_full_unstemmed Identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
title_sort identification of cerebral perfusion using arterial spin labeling in patients with seizures in acute settings.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2017-01-01
description This study aimed to explore the utility of arterial spin labeling perfusion-weighted imaging (ASL-PWI) in patients with suspected seizures in acute settings. A total of 164 patients who underwent ASL-PWI for suspected seizures in acute settings (with final diagnoses of seizure [n = 129], poststroke seizure [n = 18], and seizure mimickers [n = 17]), were included in this retrospective study. Perfusion abnormality was analyzed for: (1) pattern, (2) multifocality, and (3) atypical distribution against vascular territories. Perfusion abnormality was detected in 39% (50/129) of the seizure patients, most (94%, 47/50) being the hyperperfusion pattern. Of the patients with perfusion abnormality, multifocality or hemispheric involvement and atypical distribution against vascular territory were revealed in 46% (23/50) and 98% (49/50), respectively. In addition, seizures showed characteristic features including hyperperfusion (with or without non-territorial distribution) on ASL-PWI, thus differentiating them from poststroke seizures or seizure mimickers. In patients in whom seizure focus could be localized on both EEG and ASL-PWI, the concordance rate was 77%. The present study demonstrates that ASL-PWI can provide information regarding cerebral perfusion status in patients with seizures in acute settings and has the potential to be used as a non-invasive imaging tool to identify the cerebral perfusion in patients with seizures.
url http://europepmc.org/articles/PMC5349669?pdf=render
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