Coating the plate with antibiotic cement to treat early infection after fracture fixation with retention of the implants: a technical note

• Main Authors: Xu-sheng Qiu, Bei Cheng, Yi-xin Chen, Xiao-yang Qi, Wei-ping Sha, Guo-zhao Chen
• Format: Article
• Language: English
• Published: BMC 2018-10-01
• Series: BMC Musculoskeletal Disorders
• Subjects: Antibiotic impregnated bone cement; Local antibiotic therapy; Infection; Fracture
• Online Access: http://link.springer.com/article/10.1186/s12891-018-2285-2

Abstract Background Local antibiotic therapy has gained increasing attraction in the prevention and treatment of fracture infection. However, no reports have used local antibiotic therapy in the management of early infection after fracture fixation with retention of implants. Methods The present surgical technique report the use of antibiotic impregnated bone cement in the management of early infection after fracture fixation. Initially, the fractures were fixed with plates. The average time from initial procedure to debridement was15 days (range 9 to 25 days). The infections were treated with irrigation, debridement, and retention of the implant. The lateral surface of the plates was coated with antibiotic cement and the bone defect was filled with antibiotic cement spacer after thorough debridement. Results Ten patients underwent this technique. The mean follow-up was 2.0 years (range 6 months to 4 years). The bone union rate was 100%, and the average time to bone healing was5.5 months.There was recurrence of infection in one patient before bone healing, but the implants were left in place until bone healed, and the infection was eradicated after implant removal. Conclusion Coating the plate with antibiotic cement is a simple technique which may play a role in the management of early infection after fracture fixation.