Pathological and immunological characterization of bluetongue virus serotype 1 infection in type I interferons blocked immunocompetent adult mice

Pathological and immunological characterization of bluetongue virus serotype 1 infection in type I interferons blocked immunocompetent adult mice

Introduction: Wild-type adult mice with intact interferon (IFN) system were neither susceptible to bluetongue virus (BTV) infection nor showed signs of morbidity/mortality. Establishment of immunologically competent wild-type adult mouse model with type I IFNs blockade is necessary to assess the pat...

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Bibliographic Details
Main Authors: Mani Saminathan, Karam Pal Singh, Madhulina Maity, Sobharani Vineetha, Gundallhalli Bayyappa Manjunathareddy, Kuldeep Dhama, Yashpal Singh Malik, Muthannan Andavar Ramakrishnan, Jyoti Misri, Vivek Kumar Gupta
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Journal of Advanced Research
Subjects:
Bluetongue virus serotype 1
Adult mouse
Type I IFNs blockade
MAR1-5A3 antibody
Sequential pathology
Immune responses
Online Access:http://www.sciencedirect.com/science/article/pii/S209012322100014X

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http://www.sciencedirect.com/science/article/pii/S209012322100014X

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