Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4

Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. Inflammation is causally linked to preterm birth; therefore, finding an intervention that dampens maternal and fetal inflammatory responses may provide a new strategy to prevent adverse pregnancy and neonatal outcomes....

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Bibliographic Details
Main Authors: Valeria Garcia-Flores, Roberto Romero, Derek Miller, Yi Xu, Bogdan Done, Chharitha Veerapaneni, Yaozhu Leng, Marcia Arenas-Hernandez, Nabila Khan, Bogdan Panaitescu, Sonia S. Hassan, Luis Marat Alvarez-Salas, Nardhy Gomez-Lopez
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
amniotic fluid
clinical chorioamnionitis
fetal inflammatory response syndrome
intra-amniotic infection/inflammation
M2 macrophages
neutrophils
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01291/full

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