The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells.

<h4>Purpose</h4>Glioblastoma multiforme (GBM) is the most malignant primary type of brain tumor in adults. There has been increased focus on the immunotherapies to treat GBM patients, the therapeutic value of natural killer (NK) cells is still unknown. Programmed death-1 (PD-1) is a majo...

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Bibliographic Details
Main Authors: Bo Yuan Huang, Yi Ping Zhan, Wen Jing Zong, Chun Jiang Yu, Jun Fa Li, Yan Ming Qu, Song Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0134715