Glutationa e enzimas relacionadas: papel biológico e importância em processos patológicos Glutathione and related enzymes: biological roles and importance in pathological processes

<abstract language="eng">Glutathione (GSH) and related enzymes are pivotal for the normal functioning of several important biological processes. In this review we discuss the biosynthesis and the catalytic cycles of glutathione as well as the major GSH-related enzymes. We also presen...

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Bibliographic Details
Main Authors: Paula C. Huber, Wanda P. Almeida, Ângelo de Fátima
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2008-01-01
Series:Química Nova
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500046
Description
Summary:<abstract language="eng">Glutathione (GSH) and related enzymes are pivotal for the normal functioning of several important biological processes. In this review we discuss the biosynthesis and the catalytic cycles of glutathione as well as the major GSH-related enzymes. We also present how glutathione and enzymes are involved in cancer and the chromatographic and non-chromatographic methods used to analyze glutathione and/or its derivatives.
ISSN:0100-4042
1678-7064