Evaluation of metastatic niches in distant organs after surgical removal of tumor-bearing lymph nodes

Abstract Background Surgical removal of primary tumors can promote the incidence of tumor metastasis. However, molecular mechanisms underlying this process remain unclear. Methods We inoculated tumor cells expressing luciferase gene  into subiliac lymph node (SiLN) of the MXH10/Mo-lpr/lpr mice. The...

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Bibliographic Details
Main Authors: Jinhua Zheng, Limin Jia, Shiro Mori, Tetsuya Kodama
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-018-4538-8