Plasmodium falciparum-derived uric acid precipitates induce maturation of dendritic cells.

Malaria is characterized by cyclical fevers and high levels of inflammation, and while an early inflammatory response contributes to parasite clearance, excessive and persistent inflammation can lead to severe forms of the disease. Here, we show that Plasmodium falciparum-infected erythrocytes conta...

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Bibliographic Details
Main Authors: Diana L van de Hoef, Isabelle Coppens, Thomas Holowka, Choukri Ben Mamoun, OraLee Branch, Ana Rodriguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3565962?pdf=render