Structural and Biochemical Characterization of a Cyanobacterial PP2C Phosphatase Reveals Insights into Catalytic Mechanism and Substrate Recognition

Structural and Biochemical Characterization of a Cyanobacterial PP2C Phosphatase Reveals Insights into Catalytic Mechanism and Substrate Recognition

PP2C-type phosphatases play roles in signal transduction pathways related to abiotic stress. The cyanobacterial PP2C-type phosphatase tPphA specifically dephosphorylates the PII protein, which is a key regulator in cyanobacteria adapting to nitrogen-deficient environments. Previous studies have show...

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Bibliographic Details
Main Authors: Yunlong Si, Ye Yuan, Yue Wang, Jin Gao, Yanbo Hu, Shiqiong Feng, Jiyong Su
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Catalysts
Subjects:
PP2C variant crystal structure
PP2C inhibitor
protein chemical cross-linking
biological metal
Online Access:http://www.mdpi.com/2073-4344/6/5/60

Internet

http://www.mdpi.com/2073-4344/6/5/60

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