Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβSummary

Exposure to p40 in Early Life Prevents Intestinal Inflammation in Adulthood Through Inducing a Long-Lasting Epigenetic Imprint on TGFβSummary

Background & Aims: Colonization by gut microbiota in early life confers beneficial effects on immunity throughout the host’s lifespan. We sought to elucidate the mechanisms whereby neonatal supplementation with p40, a probiotic functional factor, reprograms intestinal epithelial cells for pr...

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Bibliographic Details
Main Authors: Yilin Deng, Oliver G. McDonald, Anna L. Means, Richard M. Peek, Jr., M. Kay Washington, Sari A. Acra, D. Brent Polk, Fang Yan
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Histone Methyltransferase
Intestinal Epithelial Cell
Probiotic Function Factor
Regulatory T Cell
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21000102

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