Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst
The study's chief purpose is to investigate multicomponent reactions synthesis of triaryl-1h imidazoles using reductive-oxidative reactions by MnO2 - FeSO4 as a catalyst.Some novel substituted imidazoles have been synthesized using MCRs, one-pot synthesis, and MnO2/FeSO4 as a catalyst; the meth...
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Islamic Azad University
2021-05-01
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doaj-c9e897c7bc4a4df2bad6a892432b15a32021-05-26T05:08:59ZengIslamic Azad UniversityJournal of Chemical Health Risks2251-67192251-67272021-05-0111222322610.22034/jchr.2021.682034682034Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a CatalystAli A.Raheem0Ali T.Saleh1University of Misan, college of Sciences, Chemistry department, Misan,62001, IraqUniversity of Misan, college of Sciences, Chemistry department, Misan,62001, IraqThe study's chief purpose is to investigate multicomponent reactions synthesis of triaryl-1h imidazoles using reductive-oxidative reactions by MnO2 - FeSO4 as a catalyst.Some novel substituted imidazoles have been synthesized using MCRs, one-pot synthesis, and MnO2/FeSO4 as a catalyst; the method involves the reaction of benzil, aromatic aldehyde, and ammonium acetate in the presence of MnO2/FeSO4 as a reductive-oxidative catalyst under mild conditions. the obtained compounds were nontoxic, excellent yields, and environmentally friendly. The compounds were elucidated using IR and 1H-NMR spectra. To satisfy the aim of the study, Reactions have been performed simply by mixing 1,2-diketone with an aldehyde and ammonium acetate in the presence of the catalytic reagent of MnO2/FeSO4. The mixture was prepared by ground them together in a mortar with a pestle at room temperature for several minutes; after that, they purified by column chromatography, 2,4,5-triaryl substituted imidazole derivatives were obtained in excellent yields.http://www.jchr.org/article_682034_4d4356bc19e0bee2bb7a5b9a33964cad.pdfmulticomponent reactionstriaryl-1h imidazolesreductive-oxidativecatalystmno2-feso4 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Ali A.Raheem Ali T.Saleh |
spellingShingle |
Ali A.Raheem Ali T.Saleh Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst Journal of Chemical Health Risks multicomponent reactions triaryl-1h imidazoles reductive-oxidative catalyst mno2-feso4 |
author_facet |
Ali A.Raheem Ali T.Saleh |
author_sort |
Ali A.Raheem |
title |
Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst |
title_short |
Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst |
title_full |
Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst |
title_fullStr |
Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst |
title_full_unstemmed |
Multicomponent Reactions Synthesis of Triaryl-1H Imidazoles Using Reductive-oxidative Reactions by MnO2-FeSO4 as a Catalyst |
title_sort |
multicomponent reactions synthesis of triaryl-1h imidazoles using reductive-oxidative reactions by mno2-feso4 as a catalyst |
publisher |
Islamic Azad University |
series |
Journal of Chemical Health Risks |
issn |
2251-6719 2251-6727 |
publishDate |
2021-05-01 |
description |
The study's chief purpose is to investigate multicomponent reactions synthesis of triaryl-1h imidazoles using reductive-oxidative reactions by MnO2 - FeSO4 as a catalyst.Some novel substituted imidazoles have been synthesized using MCRs, one-pot synthesis, and MnO2/FeSO4 as a catalyst; the method involves the reaction of benzil, aromatic aldehyde, and ammonium acetate in the presence of MnO2/FeSO4 as a reductive-oxidative catalyst under mild conditions. the obtained compounds were nontoxic, excellent yields, and environmentally friendly. The compounds were elucidated using IR and 1H-NMR spectra. To satisfy the aim of the study, Reactions have been performed simply by mixing 1,2-diketone with an aldehyde and ammonium acetate in the presence of the catalytic reagent of MnO2/FeSO4. The mixture was prepared by ground them together in a mortar with a pestle at room temperature for several minutes; after that, they purified by column chromatography, 2,4,5-triaryl substituted imidazole derivatives were obtained in excellent yields. |
topic |
multicomponent reactions triaryl-1h imidazoles reductive-oxidative catalyst mno2-feso4 |
url |
http://www.jchr.org/article_682034_4d4356bc19e0bee2bb7a5b9a33964cad.pdf |
work_keys_str_mv |
AT aliaraheem multicomponentreactionssynthesisoftriaryl1himidazolesusingreductiveoxidativereactionsbymno2feso4asacatalyst AT alitsaleh multicomponentreactionssynthesisoftriaryl1himidazolesusingreductiveoxidativereactionsbymno2feso4asacatalyst |
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