Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids

Broadly Active Antiviral Compounds Disturb Zika Virus Progeny Release Rescuing Virus-Induced Toxicity in Brain Organoids

RNA viruses have gained plenty of attention during recent outbreaks of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Zika virus (ZIKV), and Ebola virus. ZIKV is a vector borne Flavivirus that is spread by mosquitoes and it mainly infects neuronal progenitor cells. One hallmark of con...

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Bibliographic Details
Main Authors: Aleksandra Pettke, Marianna Tampere, Robin Pronk, Olov Wallner, Anna Falk, Ulrika Warpman Berglund, Thomas Helleday, Ali Mirazimi, Marjo-Riitta Puumalainen
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
Zika virus
pathogenic RNA viruses
antivirals
brain organoids
mode-of-action
Online Access:https://www.mdpi.com/1999-4915/13/1/37

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