Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms

The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmenta...

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Main Authors:	Antonio Starcevic, Jurica Zucko, Juan Diego Rojas, Janko Diminic, Damir Baranasic, Ranko Gacesa, Gabriel Padilla, Paul F. Long, John Cullum, Daslav Hranueli
Format:	Article
Language:	English
Published:	University of Zagreb 2013-01-01
Series:	Food Technology and Biotechnology
Subjects:	molecular biotechnology industrial microorganisms DNA synthesis homologous recombination , recombinant gene clusters
Online Access:	http://hrcak.srce.hr/file/146488

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spelling	doaj-ca002933408a4464a5b3ae36a1455d682020-11-25T03:14:22ZengUniversity of ZagrebFood Technology and Biotechnology1330-98621334-26062013-01-01511311Synthetic Biology: A Novel Approach for the Construction of Industrial MicroorganismsAntonio Starcevic0Jurica Zucko1Juan Diego Rojas2Janko Diminic3Damir Baranasic4Ranko Gacesa5Gabriel Padilla6Paul F. Long7John Cullum8Daslav Hranueli9Faculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaInstitute of Biomedical Sciences, University of São Paulo, São Paulo SP-CEP 05508-900, BrasilFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaInstitute of Biomedical Sciences, University of São Paulo, São Paulo SP-CEP 05508-900, BrasilKing’s College, University of London, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, UKDepartment of Genetics, University of Kaiserslautern, Postfach 3049, DE-67653 Kaiserslautern, GermanyFaculty of Food Technology and Biotechnology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, CroatiaThe recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail.http://hrcak.srce.hr/file/146488molecular biotechnologyindustrial microorganismsDNA synthesishomologous recombination, recombinant gene clusters
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Antonio Starcevic Jurica Zucko Juan Diego Rojas Janko Diminic Damir Baranasic Ranko Gacesa Gabriel Padilla Paul F. Long John Cullum Daslav Hranueli
spellingShingle	Antonio Starcevic Jurica Zucko Juan Diego Rojas Janko Diminic Damir Baranasic Ranko Gacesa Gabriel Padilla Paul F. Long John Cullum Daslav Hranueli Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms Food Technology and Biotechnology molecular biotechnology industrial microorganisms DNA synthesis homologous recombination , recombinant gene clusters
author_facet	Antonio Starcevic Jurica Zucko Juan Diego Rojas Janko Diminic Damir Baranasic Ranko Gacesa Gabriel Padilla Paul F. Long John Cullum Daslav Hranueli
author_sort	Antonio Starcevic
title	Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_short	Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_full	Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_fullStr	Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_full_unstemmed	Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms
title_sort	synthetic biology: a novel approach for the construction of industrial microorganisms
publisher	University of Zagreb
series	Food Technology and Biotechnology
issn	1330-9862 1334-2606
publishDate	2013-01-01
description	The recent achievement of synthesising a functioning bacterial chromosome marks a coming of age for engineering living organisms. In the future this should allow the construction of novel organisms to help solve the problems facing the human race, including health care, food, energy and environmental protection. In this minireview, the current state of the field is described and the role of synthetic biology in biotechnology in the short and medium term is discussed. It is particularly aimed at the needs of food technologists, nutritionists and other biotechnologists, who might not be aware of the potential significance of synthetic biology to the research and development in their fields. The potential of synthetic biology to produce interesting new polyketide compounds is discussed in detail.
topic	molecular biotechnology industrial microorganisms DNA synthesis homologous recombination , recombinant gene clusters
url	http://hrcak.srce.hr/file/146488
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Synthetic Biology: A Novel Approach for the Construction of Industrial Microorganisms

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