The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases
The prevalence of acute respiratory diseases, the particular severity of their course, as well as the frequent relapses and complications require constant search for new, more effective and safe medicines for their prevention and treatment and introduction of these drugs into clinical practice. Gene...
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doaj-ca0c9d54fa064655884521859d1c74092020-11-25T04:07:22ZukrThe State Expert Center of the Ministry of Health of UkraineФармацевтичний журнал0367-30572617-96282020-10-015516010.32352/0367-3057.5.20.06The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseasesM. Q. Gulzoda0https://orcid.org/0000-0002-1641-1555A. U. Rahmonov1https://orcid.org/0000-0002-0535-0291K. S. Makhsudov2https://orcid.org/0000-0002-0857-6181R. S. Musoev3https://orcid.org/0000-0001-5710-0027S. M. Musozoda4https://orcid.org/0000-0001-8512-8019O. S. Shpychak5https://orcid.org/0000-0002-3015-8584Avicenna Tajik State Medical University, Dushanbe, TajikistanTajik National University, Dushanbe, TajikistanTajik National University, Dushanbe, TajikistanTajik National University, Dushanbe, TajikistanTajik National University, Dushanbe, TajikistanInstitute for Advanced Studies of Pharmacy Specialists, National University of Pharmacy, Kharkіv, UkraineThe prevalence of acute respiratory diseases, the particular severity of their course, as well as the frequent relapses and complications require constant search for new, more effective and safe medicines for their prevention and treatment and introduction of these drugs into clinical practice. Generally, most of the medications used in the treatment of acute respiratory viral infections have a number of side effects. Currently, one of the promising areas of pharmacy is the study of biologically active substances, the medicinal plant raw material, and production of extracts and herbal medicines based on them. Objective – pharmaceutical development of a scientifically based composition, technology for obtaining anti-inflammatory and antimicrobial tablets developed on the basis of a selected and standardized plant substance-a thick extract of the leaves of sage nutmeg, which grows in Tajikistan. When solving the task used the methods of evaluating the technological properties of LRS, physico-chemical properties of plant extracts, physical and technological properties of the mass for tabletting, pharmaco-technological tests of the developed tabletsa study of quantitative content of biologically active substances was determined by Pharmacopoeia methods. The developed solid dosage form with thick extract of sage leaves can be registered as a medicinal product, and the developed technology of tablets with thick extract of sage leaves can be of interest to manufacturers of medicinal products from plant raw materials. The developed methods can be used in laboratories for the detection and quantitative determination of BAS in plant raw materials of Clary sage leaves and medicinal products from this LRS. Thus, based on the results of pharmacological and technological research, we have developed a technology for obtaining a thick extract of sage nutmeg and tablets based on it for the treatment of otolaryngological diseases, which in turn is of interest for further research of the developed drug and its introduction into production.https://pharmj.org.ua/index.php/journal/article/view/1063/991tabletssolid dosage formpharmaco-technological characteristicsotolaryngological diseases |
collection |
DOAJ |
language |
Ukrainian |
format |
Article |
sources |
DOAJ |
author |
M. Q. Gulzoda A. U. Rahmonov K. S. Makhsudov R. S. Musoev S. M. Musozoda O. S. Shpychak |
spellingShingle |
M. Q. Gulzoda A. U. Rahmonov K. S. Makhsudov R. S. Musoev S. M. Musozoda O. S. Shpychak The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases Фармацевтичний журнал tablets solid dosage form pharmaco-technological characteristics otolaryngological diseases |
author_facet |
M. Q. Gulzoda A. U. Rahmonov K. S. Makhsudov R. S. Musoev S. M. Musozoda O. S. Shpychak |
author_sort |
M. Q. Gulzoda |
title |
The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
title_short |
The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
title_full |
The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
title_fullStr |
The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
title_full_unstemmed |
The pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
title_sort |
pharmaco-technological studies of the tablet solid dosage form for the treatment of otolarynological diseases |
publisher |
The State Expert Center of the Ministry of Health of Ukraine |
series |
Фармацевтичний журнал |
issn |
0367-3057 2617-9628 |
publishDate |
2020-10-01 |
description |
The prevalence of acute respiratory diseases, the particular severity of their course, as well as the frequent relapses and complications require constant search for new, more effective and safe medicines for their prevention and treatment and introduction of these drugs into clinical practice. Generally, most of the medications used in the treatment of acute respiratory viral infections have a number of side effects. Currently, one of the promising areas of pharmacy is the study of biologically active substances, the medicinal plant raw material, and production of extracts and herbal medicines based on them.
Objective – pharmaceutical development of a scientifically based composition, technology for obtaining anti-inflammatory and antimicrobial tablets developed on the basis of a selected and standardized plant substance-a thick extract of the leaves of sage nutmeg, which grows in Tajikistan.
When solving the task used the methods of evaluating the technological properties of LRS, physico-chemical properties of plant extracts, physical and technological properties of the mass for tabletting, pharmaco-technological tests of the developed tabletsa study of quantitative content of biologically active substances was determined by Pharmacopoeia methods.
The developed solid dosage form with thick extract of sage leaves can be registered as a medicinal product, and the developed technology of tablets with thick extract of sage leaves can be of interest to manufacturers of medicinal products from plant raw materials. The developed methods can be used in laboratories for the detection and quantitative determination of BAS in plant raw materials of Clary sage leaves and medicinal products from this LRS.
Thus, based on the results of pharmacological and technological research, we have developed a technology for obtaining a thick extract of sage nutmeg and tablets based on it for the treatment of otolaryngological diseases, which in turn is of interest for further research of the developed drug and its introduction into production. |
topic |
tablets solid dosage form pharmaco-technological characteristics otolaryngological diseases |
url |
https://pharmj.org.ua/index.php/journal/article/view/1063/991 |
work_keys_str_mv |
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