Single-particle analysis of full-length human poly(ADP-ribose) polymerase 1

Single-particle analysis of full-length human poly(ADP-ribose) polymerase 1

PolyADP-ribosylation (PARylation) is a posttranslational modification that is involved in the various cellular functions including DNA repair, genomic stability, and transcriptional regulation. PARylation is catalyzed by the poly(ADP-ribose) polymerase (PARP) family proteins, which mainly recognize...

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Bibliographic Details
Main Authors: Kenichi Kouyama, Kouta Mayanagi, Setsu Nakae, Yoshisuke Nishi, Masanao Miwa, Tsuyoshi Shirai
Format: Article
Language:English
Published: The Biophysical Society of Japan 2019-02-01
Series:Biophysics and Physicobiology
Subjects:
parp1
dna repair
electron microscopy
structural biology
Online Access:https://doi.org/10.2142/biophysico.16.0_59

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