Functional and Comparative Genomics of Hoxa2 Gene cis-Regulatory Elements: Evidence for Evolutionary Modification of Ancestral Core Element Activity

Functional and Comparative Genomics of Hoxa2 Gene cis-Regulatory Elements: Evidence for Evolutionary Modification of Ancestral Core Element Activity

Hoxa2 is an evolutionarily conserved developmental regulatory gene that functions to specify rhombomere (r) and pharyngeal arch (PA) identities throughout the Osteichthyes. Japanese medaka (Oryzias latipes) hoxa2a, like orthologous Hoxa2 genes from other osteichthyans, is expressed during embryogene...

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Bibliographic Details
Main Authors: Adam Davis, Michael C. Reubens, Edmund J. Stellwag
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Journal of Developmental Biology
Subjects:
Japanese medaka
Hox PG2 gene expression
hoxa2a
ψhoxa2b
embryonic development
cis-regulatory elements
vertebrate evolution
gene regulation
Online Access:http://www.mdpi.com/2221-3759/4/2/15

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http://www.mdpi.com/2221-3759/4/2/15

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