Endothelin-1 Antisense Oligonucleotide Suppresses the Proliferation of Glomerular Mesangial Cells Stimulated with Angiotensin-II

Endothelin-1 Antisense Oligonucleotide Suppresses the Proliferation of Glomerular Mesangial Cells Stimulated with Angiotensin-II

Antisense oligonucleotide (AON) has been applied to modern molecular pharmacology. We have previously demonstrated that angiotensin-II (Ang-II) is an active stimulator of endothelin-1 (ET-1) production in glomerular mesangial cells. This study was designed to investigate the specific effect of ET-1...

Full description

Bibliographic Details
Main Authors: Jia-Jung Lee, Shyi-Jang Shin, Yi-Wen Chiu, Hung-Chun Chen
Format: Article
Language:English
Published: Wiley 2007-04-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
angiotensin-II
antisense oligonucleotide
endothelin-1
mesangial cell
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X09703936

Similar Items

Similar Items