Endothelin-1 Antisense Oligonucleotide Suppresses the Proliferation of Glomerular Mesangial Cells Stimulated with Angiotensin-II
Antisense oligonucleotide (AON) has been applied to modern molecular pharmacology. We have previously demonstrated that angiotensin-II (Ang-II) is an active stimulator of endothelin-1 (ET-1) production in glomerular mesangial cells. This study was designed to investigate the specific effect of ET-1...
Main Authors: | Jia-Jung Lee, Shyi-Jang Shin, Yi-Wen Chiu, Hung-Chun Chen |
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Format: | Article |
Language: | English |
Published: |
Wiley
2007-04-01
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Series: | Kaohsiung Journal of Medical Sciences |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X09703936 |
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