A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection

A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection

Bibliographic Details
Main Authors: Michal eOr-Guil, Jose eFaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Immunology
Subjects:
Phylogenetic trees
somatic hypermutation
Antibody affinity maturation
selection mechanism
V gene sequences
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00237/full
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spelling doaj-ca40d0dfad5c4f2cbc31dc4d43551cef2020-11-24T23:15:45ZengFrontiers Media S.A.Frontiers in Immunology1664-32242014-05-01510.3389/fimmu.2014.0023771032A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selectionMichal eOr-Guil0Michal eOr-Guil1Jose eFaro2Jose eFaro3Jose eFaro4Humboldt University BerlinCharité - Universitätsmedizin BerlinUniversity of Vigo and Biomedical Research Center (CINBIO)Instituto Biomédico de VigoInstituto Gulbenkian de Ciênciahttp://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00237/fullPhylogenetic treessomatic hypermutationAntibody affinity maturationselection mechanismV gene sequences
collection DOAJ
language English
format Article
sources DOAJ
author Michal eOr-Guil
Michal eOr-Guil
Jose eFaro
Jose eFaro
Jose eFaro
spellingShingle Michal eOr-Guil
Michal eOr-Guil
Jose eFaro
Jose eFaro
Jose eFaro
A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
Frontiers in Immunology
Phylogenetic trees
somatic hypermutation
Antibody affinity maturation
selection mechanism
V gene sequences
author_facet Michal eOr-Guil
Michal eOr-Guil
Jose eFaro
Jose eFaro
Jose eFaro
author_sort Michal eOr-Guil
title A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
title_short A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
title_full A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
title_fullStr A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
title_full_unstemmed A major hindrance in antibody affinity maturation investigation: We never succeeded in falsifying the hypothesis of single-step selection
title_sort major hindrance in antibody affinity maturation investigation: we never succeeded in falsifying the hypothesis of single-step selection
publisher Frontiers Media S.A.
series Frontiers in Immunology
issn 1664-3224
publishDate 2014-05-01
topic Phylogenetic trees
somatic hypermutation
Antibody affinity maturation
selection mechanism
V gene sequences
url http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00237/full
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