Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity

Dengue virus-free defective interfering particles have potent and broad anti-dengue virus activity

Li et al. produce a dengue virus (DENV)-derived defective interfering particle (DIP) production cell line that can stably produce infectious virusfree DIPs. The DENV DIPs produced from this system can potently inhibit replication of all DENV serotypes in cells and have the potential to be repurposed...

Full description

Bibliographic Details
Main Authors:	Dongsheng Li, Min-Hsuan Lin, Daniel J. Rawle, Hongping Jin, Zhonglan Wu, Lu Wang, Mary Lor, Mazhar Hussain, John Aaskov, David Harrich
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-05-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-021-02064-7

Similar Items

Defective interfering viral particles in acute dengue infections.
by: Dongsheng Li, et al.
Published: (2011-01-01)

A population of bang-bang switches of defective interfering particles makes within-host dynamics of dengue virus controllable.
by: Tarunendu Mapder, et al.
Published: (2019-11-01)

Administration of Defective Virus Inhibits Dengue Transmission into Mosquitoes
by: Tarunendu Mapder, et al.
Published: (2020-05-01)

Fitness peaks of dengue virus populations.
by: Wen Jun Liu, et al.
Published: (2018-01-01)

Phylodynamic analysis of the emergence and epidemiological impact of transmissible defective dengue viruses.
by: Ruian Ke, et al.
Published: (2013-02-01)

Distribution of fitness in populations of dengue viruses.
by: Md Abu Choudhury, et al.
Published: (2014-01-01)

New Potent Inhibitors Against The Methyltransferase of Dengue Virus
by: Sih-Wei Jian, et al.
Published: (2011)

Inhibitory effect of small interfering RNA on dengue virus replication in mosquito cells
by: Li Lei, et al.
Published: (2010-10-01)

Identification of a cryptic prokaryotic promoter within the cDNA encoding the 5' end of dengue virus RNA genome.
by: Dongsheng Li, et al.
Published: (2011-01-01)

VIRUS DENGUE
by: Dewi Marbawati
Published: (2012-11-01)

VIRUS DENGUE
by: Dewi Marbawati
Published: (2012-11-01)

In-silico approaches towards the profiling of some anti-dengue virus as potent inhibitors against dengue NS-5 receptor
by: Samuel Ndaghiya Adawara, et al.
Published: (2021-09-01)

Synthetic 1,4-pyran naphthoquinones are potent inhibitors of dengue virus replication.
by: Emmerson C B da Costa, et al.
Published: (2013-01-01)

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
by: Siew Pheng Lim, et al.
Published: (2016-08-01)

Designing a polytope for use in a broad-spectrum dengue virus vaccine
by: Karimatul Himmah, M.Si, et al.
Published: (2018-04-01)

The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR.
by: Jo-Chi Kao, et al.
Published: (2018-08-01)

Dengue virus infections and anti-dengue virus activities of Andrographis paniculata
by: Mohamed Ali-Seyed, et al.
Published: (2020-01-01)

The generation of defective interfering rubella virus particles
by: Bohn, Ehleen M.
Published: (2010)

Studies on defective interfering Semliki Forest Virus
by: Barrett, Alan D. T.
Published: (1984)

Dengue Virus, Nepal
by: Basu Dev Pandey, et al.
Published: (2008-03-01)

Dengue Virus and Autophagy
by: Nicholas S. Heaton, et al.
Published: (2011-08-01)

THE SEROEPIDEMIOLOGY OF DENGUE VIRUS IN TONGKANG AND THE ESTABLISHMENTOF DENGUE VIRUS RAPID DIAGNOSIS SYSTEM
by: Mong-Ping Lin, et al.
Published: (1993)

Milk exosomes elicit a potent anti-viral activity against dengue virus
by: Afroz, S., et al.
Published: (2022)

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513
by: Wong, Yee Hwa, et al.
Published: (2018)

Studies on defective interfering particles of West Nile virus
by: Debnath, Nitish Chandra
Published: (1992)

Immunostimulatory function of the defective interfering RNA of Sendai virus
by: Ho, Ting-hin, et al.
Published: (2014)

Defective Interfering RNAs: Foes of Viruses and Friends of Virologists
by: Peter D. Nagy, et al.
Published: (2009-11-01)

Study on the mechanism of dengue virus replication: the role of proteases during dengue virus replication
by: ChiChiu, et al.
Published: (2013)

Molecular epidemiology of dengue viruses in Brazil Epidemiologia molecular dos vírus dengue no Brasil
by: Rita Maria Ribeiro Nogueira, et al.
Published: (2000-01-01)

Dengue virus-like particles mimic the antigenic properties of the infectious dengue virus envelope
by: Stefan W. Metz, et al.
Published: (2018-04-01)

Dengue Virus Type 3, South Pacific Islands, 2013
by: Van-Mai Cao-Lormeau, et al.
Published: (2014-06-01)

Genotypes of dengue virus circulate in dengue sentinel surveillance in Indonesia
by: Reni Herman, et al.
Published: (2016-12-01)

Development of dengue virus detection and quantification system using dengue protease activity of dengue virus non-structural protein 3
by: HSIEH, MING-SHU, et al.
Published: (2018)

A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus
by: Meihui Xu, et al.
Published: (2017-01-01)

Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus
by: Jiansheng Lu, et al.
Published: (2018-06-01)

Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody
by: Wen-Fan Shen, et al.
Published: (2018-10-01)

Broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics
by: Natasha D Durham, et al.
Published: (2019-12-01)

Expressing dengue virus 2 E protein for pseudotype formation of murine leukemia virus with dengue virus envelope
by: Po-Yin Lin, et al.
Published: (2005)

Hepatitis reactive to Dengue virus
by: Sarah María Regueira Betancourt, et al.
Published: (2016-02-01)

The incubation periods of Dengue viruses.
by: Miranda Chan, et al.
Published: (2012-01-01)