Modulation of the activity and arachidonic acid selectivity of group X secretory phospholipase A2 by sphingolipids

To investigate the role of sphingomyelin (SM) in the regulation of inflammatory reactions, we studied its effect on the activity and fatty acid specificity of group X secretory phospholipase A2 (sPLA2X). Compared with other phospholipases, recombinant sPLA2X released more arachidonate from HDL. Pret...

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Bibliographic Details
Main Authors: Dev K. Singh, Papasani V. Subbaiah
Format: Article
Language:English
Published: Elsevier 2007-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520432432

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