The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran
Background: Transfusion transmissible infections (TTIs) are a common complication of blood transfusion. Evaluation and monitoring the prevalence rate of TTIs in blood donors is a valuable indicator of donor selection and blood safety. We analyzed the trends of these infections among blood dono...
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Tehran University of Medical Sciences
2018-07-01
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doaj-ca92ed047a9b4800b53dd6d8d0691c4f2021-01-02T15:40:40ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932018-07-01477The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern IranSeyed Mehdi SAJJADI0Ali Akbar POURFATHOLLAH1Saeed MOHAMMADI2Bijan NOURI3Rostam HASSANZADEH4Fariba RAD5Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, IranIranian Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, IranHematology, Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Tehran, IranSocial Determinants of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, IranIranian Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, IranCellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran Background: Transfusion transmissible infections (TTIs) are a common complication of blood transfusion. Evaluation and monitoring the prevalence rate of TTIs in blood donors is a valuable indicator of donor selection and blood safety. We analyzed the trends of these infections among blood donors at Kohgiluyeh and Boyer-Ahmad transfusion service (KBTC) during 10 years. Methods: Viral screening and confirmatory tests were carried out on 180304 voluntary donations from 2005-2014. The annual prevalence rates of hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV infections per 100000 donations and 95% confidence interval were calculated. Chi-square test was applied to obtain the P-value. Results: The overall prevalence was 0.13% for HBV and 0.06% for HCV while there were only three positive cases for HIV. The annual trend fluctuated during the time period studied. Compared to first-time donors, regular and repeat donors were significantly less likely to be positive for these infections. Outstandingly, this study provides first data in TTIs seropositivity rates among blood donors in our region; surprisingly were lower compared to other reports of Iran. Conclusion: The trends of TTIs prevalence in this study provide additional evidence that safety measures employed by the KBTC have been effective in maintaining a safe blood supply. The lower prevalence of TTIs in our study compared with other Iranian studies and also the general population reflects the efficacy of donor selection and education procedures in KBTC. https://ijph.tums.ac.ir/index.php/ijph/article/view/14035Transfusion transmissible infectionsPrevalenceTrendIran |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Seyed Mehdi SAJJADI Ali Akbar POURFATHOLLAH Saeed MOHAMMADI Bijan NOURI Rostam HASSANZADEH Fariba RAD |
spellingShingle |
Seyed Mehdi SAJJADI Ali Akbar POURFATHOLLAH Saeed MOHAMMADI Bijan NOURI Rostam HASSANZADEH Fariba RAD The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran Iranian Journal of Public Health Transfusion transmissible infections Prevalence Trend Iran |
author_facet |
Seyed Mehdi SAJJADI Ali Akbar POURFATHOLLAH Saeed MOHAMMADI Bijan NOURI Rostam HASSANZADEH Fariba RAD |
author_sort |
Seyed Mehdi SAJJADI |
title |
The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran |
title_short |
The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran |
title_full |
The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran |
title_fullStr |
The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran |
title_full_unstemmed |
The Prevalence and Trends of Hepatitis B, Hepatitis C, and HIV among Voluntary Blood Donors in Kohgiluyeh and Boyer-Ahmad Transfusion Center, Southwestern Iran |
title_sort |
prevalence and trends of hepatitis b, hepatitis c, and hiv among voluntary blood donors in kohgiluyeh and boyer-ahmad transfusion center, southwestern iran |
publisher |
Tehran University of Medical Sciences |
series |
Iranian Journal of Public Health |
issn |
2251-6085 2251-6093 |
publishDate |
2018-07-01 |
description |
Background: Transfusion transmissible infections (TTIs) are a common complication of blood transfusion. Evaluation and monitoring the prevalence rate of TTIs in blood donors is a valuable indicator of donor selection and blood safety. We analyzed the trends of these infections among blood donors at Kohgiluyeh and Boyer-Ahmad transfusion service (KBTC) during 10 years.
Methods: Viral screening and confirmatory tests were carried out on 180304 voluntary donations from 2005-2014. The annual prevalence rates of hepatitis B virus (HBV), hepatitis C virus (HCV) and HIV infections per 100000 donations and 95% confidence interval were calculated. Chi-square test was applied to obtain the P-value.
Results: The overall prevalence was 0.13% for HBV and 0.06% for HCV while there were only three positive cases for HIV. The annual trend fluctuated during the time period studied. Compared to first-time donors, regular and repeat donors were significantly less likely to be positive for these infections. Outstandingly, this study provides first data in TTIs seropositivity rates among blood donors in our region; surprisingly were lower compared to other reports of Iran.
Conclusion: The trends of TTIs prevalence in this study provide additional evidence that safety measures employed by the KBTC have been effective in maintaining a safe blood supply. The lower prevalence of TTIs in our study compared with other Iranian studies and also the general population reflects the efficacy of donor selection and education procedures in KBTC.
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topic |
Transfusion transmissible infections Prevalence Trend Iran |
url |
https://ijph.tums.ac.ir/index.php/ijph/article/view/14035 |
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