Structural and resting state functional connectivity beyond the cortex
Mapping the structural and functional connectivity of the central nervous system has become a key area within neuroimaging research. While detailed network structures across the entire brain have been probed using animal models, non-invasive neuroimaging in humans has thus far been dominated by cort...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-10-01
|
Series: | NeuroImage |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811921006558 |
id |
doaj-caa3573621f24731922c3a8f7c141a71 |
---|---|
record_format |
Article |
spelling |
doaj-caa3573621f24731922c3a8f7c141a712021-09-05T04:39:28ZengElsevierNeuroImage1095-95722021-10-01240118379Structural and resting state functional connectivity beyond the cortexOlivia K. Harrison0Xavier Guell1Miriam C. Klein-Flügge2Robert L. Barry3School of Pharmacy, University of Otago, New Zealand; Translational Neuromodeling Unit, Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Switzerland; Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom; Corresponding author at: School of Pharmacy, University of Otago, New Zealand.Massachusetts General Hospital, Harvard Medical School, United States; Massachusetts Institute of Technology, United StatesWellcome Centre for Integrative Neuroimaging, Department of Experimental Psychology, University of Oxford, United KingdomAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, United States; Department of Radiology, Harvard Medical School, United States; Harvard–Massachusetts Institute of Technology Health Sciences & Technology, United StatesMapping the structural and functional connectivity of the central nervous system has become a key area within neuroimaging research. While detailed network structures across the entire brain have been probed using animal models, non-invasive neuroimaging in humans has thus far been dominated by cortical investigations. Beyond the cortex, subcortical nuclei have traditionally been less accessible due to their smaller size and greater distance from radio frequency coils. However, major neuroimaging developments now provide improved signal and the resolution required to study these structures. Here, we present an overview of the connectivity between the amygdala, brainstem, cerebellum, spinal cord and the rest of the brain. While limitations to their imaging and analyses remain, we also provide some recommendations and considerations for mapping brain connectivity beyond the cortex.http://www.sciencedirect.com/science/article/pii/S1053811921006558ConnectivityAmygdalaBrainstemCerebellumSpinal cord |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Olivia K. Harrison Xavier Guell Miriam C. Klein-Flügge Robert L. Barry |
spellingShingle |
Olivia K. Harrison Xavier Guell Miriam C. Klein-Flügge Robert L. Barry Structural and resting state functional connectivity beyond the cortex NeuroImage Connectivity Amygdala Brainstem Cerebellum Spinal cord |
author_facet |
Olivia K. Harrison Xavier Guell Miriam C. Klein-Flügge Robert L. Barry |
author_sort |
Olivia K. Harrison |
title |
Structural and resting state functional connectivity beyond the cortex |
title_short |
Structural and resting state functional connectivity beyond the cortex |
title_full |
Structural and resting state functional connectivity beyond the cortex |
title_fullStr |
Structural and resting state functional connectivity beyond the cortex |
title_full_unstemmed |
Structural and resting state functional connectivity beyond the cortex |
title_sort |
structural and resting state functional connectivity beyond the cortex |
publisher |
Elsevier |
series |
NeuroImage |
issn |
1095-9572 |
publishDate |
2021-10-01 |
description |
Mapping the structural and functional connectivity of the central nervous system has become a key area within neuroimaging research. While detailed network structures across the entire brain have been probed using animal models, non-invasive neuroimaging in humans has thus far been dominated by cortical investigations. Beyond the cortex, subcortical nuclei have traditionally been less accessible due to their smaller size and greater distance from radio frequency coils. However, major neuroimaging developments now provide improved signal and the resolution required to study these structures. Here, we present an overview of the connectivity between the amygdala, brainstem, cerebellum, spinal cord and the rest of the brain. While limitations to their imaging and analyses remain, we also provide some recommendations and considerations for mapping brain connectivity beyond the cortex. |
topic |
Connectivity Amygdala Brainstem Cerebellum Spinal cord |
url |
http://www.sciencedirect.com/science/article/pii/S1053811921006558 |
work_keys_str_mv |
AT oliviakharrison structuralandrestingstatefunctionalconnectivitybeyondthecortex AT xavierguell structuralandrestingstatefunctionalconnectivitybeyondthecortex AT miriamckleinflugge structuralandrestingstatefunctionalconnectivitybeyondthecortex AT robertlbarry structuralandrestingstatefunctionalconnectivitybeyondthecortex |
_version_ |
1717814699815337984 |