Serine Hydroxymethyltransferase ShrA (PA2444) Controls Rugose Small-Colony Variant Formation in Pseudomonas aeruginosa

Serine Hydroxymethyltransferase ShrA (PA2444) Controls Rugose Small-Colony Variant Formation in Pseudomonas aeruginosa

Pseudomonas aeruginosa causes many biofilm infections, and the rugose small-colony variants (RSCVs) of this bacterium are important for infection. We found here that inactivation of PA2444, which we determined to be a serine hydroxymethyltransferase (SHMT), leads to the RSCV phenotype of P. aerugino...

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Bibliographic Details
Main Authors:	Mingming Pu, Lili Sheng, Sooyeon Song, Ting Gong, Thomas K. Wood
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-02-01
Series:	Frontiers in Microbiology
Subjects:	rugose small colony variants serine hydroxymethyltransferase Pseudomonas aeruginosa biofilm formation
Online Access:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00315/full

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