Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons

Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons

Summary Kallmann's syndrome is caused by the failure of olfactory axons and gonadotropin-releasing hormone (GnRH) neurons to enter the embryonic forebrain, resulting in anosmia and sterility. Sox10 mutations have been associated with Kallmann's syndrome phenotypes, but their effect on olfa...

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Bibliographic Details
Main Authors: Perrine Barraud, James A. St John, C. Claus Stolt, Michael Wegner, Clare V. H. Baker
Format: Article
Language:English
Published: The Company of Biologists 2013-06-01
Series:Biology Open
Subjects:
Sox10
Olfactory ensheathing glia
GnRH neurons
Kallmann's syndrome
Online Access:http://bio.biologists.org/content/2/7/750

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