Following the flux of long-chain bases through the sphingolipid pathway in vivo using mass spectrometry[S]
Sphingolipids are essential components of the plasma membrane. Their synthesis is tightly controlled by regulatory proteins, which impinge on the rate-limiting step of the pathway, the condensation of serine and palmitoyl-CoA to long-chain base (LCB). The subsequent conversion of LCB to ceramide by...
Main Authors: | Fernando Martínez-Montañés, Roger Schneiter |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-05-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520309925 |
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