Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Endoplasmic Reticulum Stress and Immunological Stress in Pathogenesis of Alzheimer’s Disease
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, accompanied by neuronal loss and the formation of senile plaques in the brain. Glial cells, such as microglia, have been shown to be activated and induce chronic inflammatory responses in AD brain. The endoplasmic reticulum (ER)...
Main Authors: | Toru Hosoi, Koichiro Ozawa |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319305560 |
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