HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo.

HSP90 inhibition suppresses lipopolysaccharide-induced lung inflammation in vivo.

Inflammation is an important component of cancer diathesis and treatment-refractory inflammation is a feature of many chronic degenerative lung diseases. HSP90 is a 90kDa protein which functions as an ATP-dependent molecular chaperone that regulates the signalling conformation and expression of mult...

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Main Authors: Andrew Lilja, Clare E Weeden, Kate McArthur, Thao Nguyen, Alastair Donald, Zi Xin Wong, Lovisa Dousha, Steve Bozinovski, Ross Vlahos, Christopher J Burns, Marie-Liesse Asselin-Labat, Gary P Anderson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4304786?pdf=render

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http://europepmc.org/articles/PMC4304786?pdf=render

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