Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2âDeficient Mice Develop PancreatitisSummary

Background & Aims: The pathogenic mechanism of pancreatitis is poorly understood. Recent evidence implicates defective autophagy in pancreatitis responses; however, the pathways mediating impaired autophagy in pancreas remain largely unknown. Here, we investigate the role of lysosome associated...

Full description

Bibliographic Details
Main Authors: Olga A. Mareninova, Matthias Sendler, Sudarshan Ravi Malla, Iskandar Yakubov, Samuel W. French, Elmira Tokhtaeva, Olga Vagin, Viola Oorschot, Renate Lüllmann-Rauch, Judith Blanz, David Dawson, Judith Klumperman, Markus M. Lerch, Julia Mayerle, Ilya Gukovsky, Anna S. Gukovskaya
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X15001290