Molecular Network Analysis Suggests a Logical Hypothesis for the Pathological Role of C9orf72 in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
Background Expanded GGGGCC hexanucleotide repeats, ranging from hundreds to thousands in number, located in the noncoding region of the chromosome 9 open reading frame 72 ( C9orf72 ) gene represent the most common genetic abnormality for familial and sporadic amyotrophic lateral sclerosis (ALS) and...
Main Authors: | Jun-Ichi Satoh, Yoji Yamamoto, Shouta Kitano, Mika Takitani, Naohiro Asahina, Yoshihiro Kino |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-01-01
|
Series: | Journal of Central Nervous System Disease |
Online Access: | https://doi.org/10.4137/JCNSD.S18103 |
Similar Items
-
Molecular Network Analysis Suggests a Logical Hypothesis for the Pathological Role of C9orf72 in Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
by: Jun-ichi Satoh, et al.
Published: (2014-08-01) -
Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72
by: Shouta Kitano, et al.
Published: (2015-06-01) -
Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72
by: Shouta Kitano, et al.
Published: (2015-01-01) -
A Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis
by: Jun-ichi Satoh, et al.
Published: (2015-05-01) -
A Comprehensive Profile of ChIP-Seq-Based Olig2 Target Genes in Motor Neuron Progenitor Cells Suggests the Possible Involvement of Olig2 in the Pathogenesis of Amyotrophic Lateral Sclerosis
by: Jun-Ichi Satoh, et al.
Published: (2015-01-01)