Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells

Tamoxifen is the first line drug used in the treatment of estrogen receptor-positive (ER+) breast cancer. The development of multidrug resistance (MDR) to tamoxifen remains a major challenge in the treatment of cancer. One of the mechanisms related to MDR is decrease of drug influx via overexpressio...

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Bibliographic Details
Main Authors: Desak Gede Budi Krisnamurti, Melva Louisa, Erlia Anggraeni, Septelia Inawati Wanandi
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2016/6702424

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