Transcriptome profiling of human thymic CD4+ and CD8+ T cells compared to primary peripheral T cells
Abstract Background The thymus is a highly specialized organ of the immune system where T cell precursors develop and differentiate into self-tolerant CD4+ or CD8+ T cells. No studies to date have investigated how the human transcriptome profiles differ, between T cells still residing in the thymus...
Main Authors: | Hanna Helgeland, Ingvild Gabrielsen, Helle Akselsen, Arvind Y. M. Sundaram, Siri Tennebø Flåm, Benedicte Alexandra Lie |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-020-6755-1 |
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