Cell-Free Coelomic Fluid Extracts of the Sea Urchin <i>Arbacia lixula</i> Impair Mitochondrial Potential and Cell Cycle Distribution and Stimulate Reactive Oxygen Species Production and Autophagic Activity in Triple-Negative MDA-MB231 Breast Cancer Cells

Cell-Free Coelomic Fluid Extracts of the Sea Urchin <i>Arbacia lixula</i> Impair Mitochondrial Potential and Cell Cycle Distribution and Stimulate Reactive Oxygen Species Production and Autophagic Activity in Triple-Negative MDA-MB231 Breast Cancer Cells

Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell growth, we explored the in vitro effects of crud...

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Bibliographic Details
Main Authors: Claudio Luparello, Debora Ragona, Dalia Maria Lucia Asaro, Valentina Lazzara, Federica Affranchi, Vincenzo Arizza, Mirella Vazzana
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Marine Science and Engineering
Subjects:
echinoderm
breast cancer
cytotoxicity
Online Access:https://www.mdpi.com/2077-1312/8/4/261

Internet

https://www.mdpi.com/2077-1312/8/4/261

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