Palmoplantar Pustulosis-like Eruption Induced by Baricitinib for Treatment of Rheumatoid Arthritis

Palmoplantar Pustulosis-like Eruption Induced by Baricitinib for Treatment of Rheumatoid Arthritis

Objectives: Baricitinib is an orally active Janus kinase (JAK) inhibitor used in the treatment of moderate to severe rheumatoid arthritis (RA). Materials and methods: Here, we report the case of a 56-year-old Caucasian male diagnosed with RA who developed palmoplantar pustulosis (PPP) while being t...

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Bibliographic Details
Main Authors: Dimitra Koumaki, Vasiliki Koumaki, George Bertsias, Eleni Lagoudaki
Format: Article
Language:English
Published: SMC MEDIA SRL 2019-12-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
palmoplantar pustulosis
baricitinib
rheumatoid arthritis
cutaneous side effects
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/1383
Description
Summary:Objectives: Baricitinib is an orally active Janus kinase (JAK) inhibitor used in the treatment of moderate to severe rheumatoid arthritis (RA). Materials and methods: Here, we report the case of a 56-year-old Caucasian male diagnosed with RA who developed palmoplantar pustulosis (PPP) while being treated with baricitinib. Results: The patient’s PPP resolved after discontinuation of baricitinib and recurred when this was restarted. Based on causality assessment, it was considered a drug-induced PPP. Conclusion: To the authors’ knowledge, this is the first case of baricitinib-induced PPP.
ISSN:2284-2594

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