Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment

Synthesis, physicochemical properties and ocular pharmacokinetics of thermosensitive in situ hydrogels for ganciclovir in cytomegalovirus retinitis treatment

Ganciclovir (GCV) is one of the most widely used antiviral drugs for the treatment of cytomegalovirus (CMV) retinitis. In this context, the aim of this study was to design in situ thermosensitive hydrogels for GCV ocular delivery by intravitreal injection to achieve sustained drug release behavior a...

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Bibliographic Details
Main Authors:	Qiyue Wang, Chunmeng Sun, Bohui Xu, Jiasheng Tu, Yan Shen
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2018-01-01
Series:	Drug Delivery
Subjects:	in situ hydrogels pbla-peg-pbla thermosensitive ganciclovir intravitreal injection
Online Access:	http://dx.doi.org/10.1080/10717544.2017.1413448

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