Activation of Egr-1 in human lung epithelial cells exposed to silica through MAPKs signaling pathways.
The alveolar type II epithelial cell, regarded historically as a key target cell in initial injury by silica, now appears to be important in both defense from lung damage as well as elaboration of chemokines and cytokines. The molecular basis for silica-induced epithelial cell injury is poorly under...
Main Authors: | Ling Chu, Tiansheng Wang, Yongbin Hu, Yonghong Gu, Zanshan Su, Haiying Jiang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3715534?pdf=render |
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