Translational Significance for Tumor Metastasis of Tumor-Associated Macrophages and Epithelial–Mesenchymal Transition

Translational Significance for Tumor Metastasis of Tumor-Associated Macrophages and Epithelial–Mesenchymal Transition

The tumor microenvironment determines development and progression of many cancers. Epithelial–mesenchymal transition (EMT) is fundamental to tumor progression and metastasis not only by increasing invasiveness but also by increasing resistance to cell death, senescence, and various cancer therapies;...

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Bibliographic Details
Main Authors: Wenzhe Song, Roberta Mazzieri, Tao Yang, Glenda C. Gobe
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
tumor-associated macrophages
epithelial–mesenchymal transition
metastasis
EMT
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01106/full

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