Effectiveness of Core-Shell Nanofibers Incorporating Amphotericin B by Solution Blow Spinning Against Leishmania and Candida Species

Effectiveness of Core-Shell Nanofibers Incorporating Amphotericin B by Solution Blow Spinning Against Leishmania and Candida Species

The aim of this study was to develop polymeric nanofibers for controlled administration of Amphotericin B (AmpB), using the solution centrifugation technique, characterizing its microstructural and physical properties, release rate, and activity against Leishmania and Candida species. The core-shell...

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Bibliographic Details
Main Authors: Ingrid Morgana Fernandes Gonçalves, Ítalo Martins Rocha, Emanuene Galdino Pires, Isis de Araújo Ferreira Muniz, Panmella Pereira Maciel, Jefferson Muniz de Lima, Iêda Maria Garcia dos Santos, Roberta Bonan Dantas Batista, Eudes Leonnan Gomes de Medeiros, Eliton Souto de Medeiros, Juliano Elvis de Oliveira, Luiz Ricardo Goulart, Paulo Rogério Ferreti Bonan, Lúcio Roberto Cançado Castellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
amphotericin B
nanofibers
drug delivery systems
candidiasis
leishmaniasis
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.571821/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.571821/full

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