New insight into the application of outer membrane vesicles of Gram-negative bacteria

This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and ap...

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Main Authors: A Fateh, F Vaziri, F Rahimi Janani, S Ahmadi Badi, M Ghazanfari, M Davari, A Arsang, SD Siadat
Format: Article
Language:English
Published: Pasteur Institute of Iran 2016-05-01
Series:Vaccine Research
Subjects:
omv
Online Access:http://vacres.pasteur.ac.ir/article-1-77-en.html
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spelling doaj-cbcf3e28a2ac4d7b92e7186440d5da792020-11-25T03:07:57ZengPasteur Institute of IranVaccine Research2383-28192423-49232016-05-013114New insight into the application of outer membrane vesicles of Gram-negative bacteriaA Fateh0F Vaziri1F Rahimi Janani2S Ahmadi Badi3M Ghazanfari4M Davari5A Arsang6SD Siadat7 Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran, Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran, Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran, Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran Mycobacteriology and Pulmonary Research Department, Pasteur Institute of Iran. Tehran, Iran, Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV carriers in conjugated vaccines as well as in drug vehicles and delivery systems are discussed. Finally, new applications of these macromolecules as biotechnological tools are briefly presented.http://vacres.pasteur.ac.ir/article-1-77-en.htmlomvvaccinedrug vehiclesdelivery systems.
collection DOAJ
language English
format Article
sources DOAJ
author A Fateh
F Vaziri
F Rahimi Janani
S Ahmadi Badi
M Ghazanfari
M Davari
A Arsang
SD Siadat
spellingShingle A Fateh
F Vaziri
F Rahimi Janani
S Ahmadi Badi
M Ghazanfari
M Davari
A Arsang
SD Siadat
New insight into the application of outer membrane vesicles of Gram-negative bacteria
Vaccine Research
omv
vaccine
drug vehicles
delivery systems.
author_facet A Fateh
F Vaziri
F Rahimi Janani
S Ahmadi Badi
M Ghazanfari
M Davari
A Arsang
SD Siadat
author_sort A Fateh
title New insight into the application of outer membrane vesicles of Gram-negative bacteria
title_short New insight into the application of outer membrane vesicles of Gram-negative bacteria
title_full New insight into the application of outer membrane vesicles of Gram-negative bacteria
title_fullStr New insight into the application of outer membrane vesicles of Gram-negative bacteria
title_full_unstemmed New insight into the application of outer membrane vesicles of Gram-negative bacteria
title_sort new insight into the application of outer membrane vesicles of gram-negative bacteria
publisher Pasteur Institute of Iran
series Vaccine Research
issn 2383-2819
2423-4923
publishDate 2016-05-01
description This review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (OMVs), originating from the surface of Gram negative bacteria including their outer membrane proteins and lipopolysaccharides. Moreover, the functional roles and applications of OMVs in medical research such as OMV-based vaccines, OMV adjuvants properties, OMV carriers in conjugated vaccines as well as in drug vehicles and delivery systems are discussed. Finally, new applications of these macromolecules as biotechnological tools are briefly presented.
topic omv
vaccine
drug vehicles
delivery systems.
url http://vacres.pasteur.ac.ir/article-1-77-en.html
work_keys_str_mv AT afateh newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT fvaziri newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT frahimijanani newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT sahmadibadi newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT mghazanfari newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT mdavari newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT aarsang newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
AT sdsiadat newinsightintotheapplicationofoutermembranevesiclesofgramnegativebacteria
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