ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells.

Interferon α (IFNα) counteracts viral infections by activating various IFNα-stimulated genes (ISGs). These genes encode proteins that block viral transport into the host cell and inhibit viral replication, gene transcription and translation. Due to the existence of 14 different, highly homologous is...

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Bibliographic Details
Main Authors: Konrad Büssow, Philipp Themann, Sabine Luu, Paul Pentrowski, Claudia Harting, Mira Majewski, Veith Vollmer, Mario Köster, Martina Grashoff, Rainer Zawatzky, Joop Van den Heuvel, Andrea Kröger, Thomas Böldicke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215062