Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up
<p>Abstract</p> <p>Objectives</p> <p>To quantify the improvement in health outcomes in patients after total knee replacement (TKR).</p> <p>Methods</p> <p>This was a two-year non-randomized prospective observational study in knee osteoarthritis (O...
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doaj-cbe1f5ba4ba34ff2955d6d50a4bc30022020-11-24T20:47:08ZengBMCHealth and Quality of Life Outcomes1477-75252010-08-01818710.1186/1477-7525-8-87Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-upXie FengLo Ngai-NungPullenayegum Eleanor MTarride Jean-EricO'Reilly Daria JGoeree RonLee Hin-Peng<p>Abstract</p> <p>Objectives</p> <p>To quantify the improvement in health outcomes in patients after total knee replacement (TKR).</p> <p>Methods</p> <p>This was a two-year non-randomized prospective observational study in knee osteoarthritis (OA) patients undergone TKR. Patients were interviewed one week before, six months after, and two years after surgery using a standardized questionnaire including the SF-36, the Oxford Knee Score (OKS), and the Knee Society Clinical Rating Scale (KSS). A generalized estimating equation (GEE) model was used to estimate the magnitudes of the changes with and without the adjustment of age, ethnicity, BMI, and years with OA.</p> <p>Results</p> <p>A total of 298 (at baseline), 176 (at six-months), and 111 (at two-years) eligible patients were included in the analyses. All the scores changed significantly over time, with the exception of SF-36 social functioning, vitality, and mental health. With the adjustment of covariates, the magnitude of changes in these scores was similar to those without the adjustment.</p> <p>Conclusions</p> <p>Both general and knee-specific physical functioning had been significantly improved after TKR, while other health domains have not been substantially improved after the surgery.</p> http://www.hqlo.com/content/8/1/87 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Xie Feng Lo Ngai-Nung Pullenayegum Eleanor M Tarride Jean-Eric O'Reilly Daria J Goeree Ron Lee Hin-Peng |
spellingShingle |
Xie Feng Lo Ngai-Nung Pullenayegum Eleanor M Tarride Jean-Eric O'Reilly Daria J Goeree Ron Lee Hin-Peng Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up Health and Quality of Life Outcomes |
author_facet |
Xie Feng Lo Ngai-Nung Pullenayegum Eleanor M Tarride Jean-Eric O'Reilly Daria J Goeree Ron Lee Hin-Peng |
author_sort |
Xie Feng |
title |
Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
title_short |
Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
title_full |
Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
title_fullStr |
Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
title_full_unstemmed |
Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
title_sort |
evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up |
publisher |
BMC |
series |
Health and Quality of Life Outcomes |
issn |
1477-7525 |
publishDate |
2010-08-01 |
description |
<p>Abstract</p> <p>Objectives</p> <p>To quantify the improvement in health outcomes in patients after total knee replacement (TKR).</p> <p>Methods</p> <p>This was a two-year non-randomized prospective observational study in knee osteoarthritis (OA) patients undergone TKR. Patients were interviewed one week before, six months after, and two years after surgery using a standardized questionnaire including the SF-36, the Oxford Knee Score (OKS), and the Knee Society Clinical Rating Scale (KSS). A generalized estimating equation (GEE) model was used to estimate the magnitudes of the changes with and without the adjustment of age, ethnicity, BMI, and years with OA.</p> <p>Results</p> <p>A total of 298 (at baseline), 176 (at six-months), and 111 (at two-years) eligible patients were included in the analyses. All the scores changed significantly over time, with the exception of SF-36 social functioning, vitality, and mental health. With the adjustment of covariates, the magnitude of changes in these scores was similar to those without the adjustment.</p> <p>Conclusions</p> <p>Both general and knee-specific physical functioning had been significantly improved after TKR, while other health domains have not been substantially improved after the surgery.</p> |
url |
http://www.hqlo.com/content/8/1/87 |
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