Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation
BackgroundIn persons with Parkinson’s disease (PD), gait dysfunctions are often associated with abnormal neuromuscular function. Physical therapy combined with auditory stimulation has been recently shown to improve motor function and gait kinematic patterns; however, the underlying neuromuscular co...
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doaj-cbea9cf3995a418989247caf7341d5ff2020-11-24T20:48:21ZengFrontiers Media S.A.Frontiers in Neurology1664-22952018-04-01910.3389/fneur.2018.00211345971Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory StimulationChristopher A. Bailey0Federica Corona1Mauro Murgia2Roberta Pili3Massimiliano Pau4Julie N. Côté5Department of Kinesiology and Physical Education, McGill University, Montreal, QC, CanadaDepartment of Mechanical, Chemical and Materials Engineering, University of Cagliari, Cagliari, ItalyDepartment of Life Sciences, University of Trieste, Trieste, ItalyDepartment of Surgical Sciences, University of Cagliari, Cagliari, ItalyDepartment of Mechanical, Chemical and Materials Engineering, University of Cagliari, Cagliari, ItalyDepartment of Kinesiology and Physical Education, McGill University, Montreal, QC, CanadaBackgroundIn persons with Parkinson’s disease (PD), gait dysfunctions are often associated with abnormal neuromuscular function. Physical therapy combined with auditory stimulation has been recently shown to improve motor function and gait kinematic patterns; however, the underlying neuromuscular control patterns leading to this improvement have never been identified.Objectives(1) Assess the relationships between motor dysfunction and lower limb muscle activity during gait in persons with PD; (2) Quantify the effects of physical therapy with rhythmic auditory stimulation (PT-RAS) on lower limb muscle activity during gait in persons with PD.MethodsParticipants (15 with PD) completed a 17-week intervention of PT-RAS. Gait was analyzed at baseline, after 5 weeks of supervised treatment (T5), and at a 12-week follow-up (T17). For each session, motor dysfunction was scored using the United Parkinson Disease Rating Scale, and muscle activation amplitude, modulation, variability, and asymmetry were measured for the rectus femoris, tibialis anterior, and gastrocnemius lateralis (GL). Spearman correlation analyses assessed the relationships between dysfunction and muscle activity, and mixed effect models (session × muscle) tested for intervention effects.ResultsPT-RAS was effective in decreasing motor dysfunction by an average of 23 (T5) to 36% (T17). Higher GL activity variability and bilateral asymmetry were correlated to higher dysfunction (ρ = 0.301 −0.610, p’s < 0.05) and asymmetry significantly decreased during the intervention (p < 0.05).ConclusionResults suggest that gait motor dysfunction in PD may be explained by neuromuscular control impairments of GL that go beyond simple muscle amplitude change. Physical therapy with RAS improves bilateral symmetry, but its effect on muscle variability requires future investigation.http://journal.frontiersin.org/article/10.3389/fneur.2018.00211/fullelectromyogram variabilityelectromyogram asymmetrymotor dysfunctiongaitrhythmic auditory stimulation |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Christopher A. Bailey Federica Corona Mauro Murgia Roberta Pili Massimiliano Pau Julie N. Côté |
spellingShingle |
Christopher A. Bailey Federica Corona Mauro Murgia Roberta Pili Massimiliano Pau Julie N. Côté Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation Frontiers in Neurology electromyogram variability electromyogram asymmetry motor dysfunction gait rhythmic auditory stimulation |
author_facet |
Christopher A. Bailey Federica Corona Mauro Murgia Roberta Pili Massimiliano Pau Julie N. Côté |
author_sort |
Christopher A. Bailey |
title |
Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation |
title_short |
Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation |
title_full |
Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation |
title_fullStr |
Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation |
title_full_unstemmed |
Electromyographical Gait Characteristics in Parkinson’s Disease: Effects of Combined Physical Therapy and Rhythmic Auditory Stimulation |
title_sort |
electromyographical gait characteristics in parkinson’s disease: effects of combined physical therapy and rhythmic auditory stimulation |
publisher |
Frontiers Media S.A. |
series |
Frontiers in Neurology |
issn |
1664-2295 |
publishDate |
2018-04-01 |
description |
BackgroundIn persons with Parkinson’s disease (PD), gait dysfunctions are often associated with abnormal neuromuscular function. Physical therapy combined with auditory stimulation has been recently shown to improve motor function and gait kinematic patterns; however, the underlying neuromuscular control patterns leading to this improvement have never been identified.Objectives(1) Assess the relationships between motor dysfunction and lower limb muscle activity during gait in persons with PD; (2) Quantify the effects of physical therapy with rhythmic auditory stimulation (PT-RAS) on lower limb muscle activity during gait in persons with PD.MethodsParticipants (15 with PD) completed a 17-week intervention of PT-RAS. Gait was analyzed at baseline, after 5 weeks of supervised treatment (T5), and at a 12-week follow-up (T17). For each session, motor dysfunction was scored using the United Parkinson Disease Rating Scale, and muscle activation amplitude, modulation, variability, and asymmetry were measured for the rectus femoris, tibialis anterior, and gastrocnemius lateralis (GL). Spearman correlation analyses assessed the relationships between dysfunction and muscle activity, and mixed effect models (session × muscle) tested for intervention effects.ResultsPT-RAS was effective in decreasing motor dysfunction by an average of 23 (T5) to 36% (T17). Higher GL activity variability and bilateral asymmetry were correlated to higher dysfunction (ρ = 0.301 −0.610, p’s < 0.05) and asymmetry significantly decreased during the intervention (p < 0.05).ConclusionResults suggest that gait motor dysfunction in PD may be explained by neuromuscular control impairments of GL that go beyond simple muscle amplitude change. Physical therapy with RAS improves bilateral symmetry, but its effect on muscle variability requires future investigation. |
topic |
electromyogram variability electromyogram asymmetry motor dysfunction gait rhythmic auditory stimulation |
url |
http://journal.frontiersin.org/article/10.3389/fneur.2018.00211/full |
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