Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1.

BACKGROUND: Melanin-concentrating hormone receptor 1 (MCHR1) plays a significant role in regulation of energy balance, food intake, physical activity and body weight in humans and rodents. Several association studies for human obesity showed contrary results concerning the SNPs rs133072 (G/A) and rs...

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Bibliographic Details
Main Authors: Stefanie Stepanow, Kathrin Reichwald, Klaus Huse, Ulrike Gausmann, Almut Nebel, Philip Rosenstiel, Martin Wabitsch, Pamela Fischer-Posovszky, Matthias Platzer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3102661?pdf=render