The Tm7sf2 Gene Deficiency Protects Mice against Endotoxin-Induced Acute Kidney Injury.

Cholesterol is essential for diverse cellular functions and cellular and whole-body cholesterol homeostasis is highly controlled. Cholesterol can also influence cellular susceptibility to injury. The connection between cholesterol metabolism and inflammation is exemplified by the Tm7sf2 gene, the ab...

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Bibliographic Details
Main Authors: Leonardo Gatticchi, Ilaria Bellezza, Rachele Del Sordo, Matthew J Peirce, Angelo Sidoni, Rita Roberti, Alba Minelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4635018?pdf=render