Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

Isolation and Structural Determination of the First 8-epi-type Tetrodotoxin Analogs from the Newt, Cynops ensicauda popei, and Comparison of Tetrodotoxin Analogs Profiles of This Newt and the Puffer Fish, Fugu poecilonotus

Identification of new tetrodotoxin (TTX) analogs from TTX-possessing animals might provide insight into its biosynthesis and metabolism. In this study, four new analogs, 8-epi-5,6,11-trideoxyTTX, 4,9-anhydro-8-epi-5,6,11-trideoxyTTX, 1-hydroxy-8-epi-5,6,11-trideoxyTTX, and 1-hydroxy-4,4a-anhydro-8-e...

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Bibliographic Details
Main Authors: Mari Yotsu-Yamashita, Yuta Kudo, Takeshi Yasumoto, Keiichi Konoki, Yuko Cho
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Marine Drugs
Subjects:
tetrodotoxin
8-epi-5,6,11-trideoxytetrodotoxin
puffer fish
newt
LC/MS
Online Access:http://www.mdpi.com/1660-3397/10/3/655/

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