Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory

Cystic fibrosis carriership and tuberculosis: hints toward an evolutionary selective advantage based on data from the Brazilian territory

Abstract Background The reason why Cystic Fibrosis (CF) is the most common fatal genetic disease among Caucasians has been incompletely studied. We aimed at deepening the hypothesis that CF carriers have a relative protection against Mycobacterium tuberculosis (Mtb) infection. Methods Applying spati...

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Bibliographic Details
Main Authors: Lander Bosch, Barbara Bosch, Kris De Boeck, Tim Nawrot, Isabelle Meyts, Dominique Vanneste, Cleonice Alexandre Le Bourlegat, Julio Croda, Luiz Vicente Ribeiro Ferreira da Silva Filho
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Infectious Diseases
Subjects:
Cystic fibrosis
Tuberculosis
Spatial epidemiology
Brazil
Resistance genetics
Online Access:http://link.springer.com/article/10.1186/s12879-017-2448-z

Internet

http://link.springer.com/article/10.1186/s12879-017-2448-z

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