Deletion of C1ql1 Causes Hearing Loss and Abnormal Auditory Nerve Fibers in the Mouse Cochlea

Deletion of C1ql1 Causes Hearing Loss and Abnormal Auditory Nerve Fibers in the Mouse Cochlea

Complement C1q Like 1 (C1QL1), a secreted component of C1Q-related protein, is known to play an important role in synaptic maturation, regulation, and maintenance in the central nervous system. C1ql1 is expressed in adult cochlear inner and outer hair cells (IHCs and OHCs) with preferential expressi...

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Bibliographic Details
Main Authors: Yue Qi, Wei Xiong, Shukui Yu, Zhengde Du, Tengfei Qu, Lu He, Wei Wei, Lingjun Zhang, Ke Liu, Yi Li, David Z. He, Shusheng Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
C1QL1
hair cells
innervation
hearing loss
mice
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.713651/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2021.713651/full

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