Molecular analysis of rpoB gene mutations in rifampicin resistant Mycobacterium tuberculosis isolates by multiple allele specific polymerase chain reaction in Puducherry, South India

Molecular analysis of rpoB gene mutations in rifampicin resistant Mycobacterium tuberculosis isolates by multiple allele specific polymerase chain reaction in Puducherry, South India

Summary: Background: rpoB gene mutations in Mycobacterium tuberculosis (MTB) make the bacteria resistant to rifampicin. Thus, these mutations are surrogate markers for multi-drug resistance (MDR). The objective of this study was to evaluate an allele-specific multiplex-polymerase chain reaction (MA...

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Bibliographic Details
Main Authors: Ravibalan Thirumurugan, Maruthai Kathirvel, Kommoju Vallayyachari, Kesavan Surendar, Antony V. Samrot, Muthuraj Muthaiah
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Journal of Infection and Public Health
Online Access:http://www.sciencedirect.com/science/article/pii/S1876034115001008

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http://www.sciencedirect.com/science/article/pii/S1876034115001008

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