Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts

Exosomal miRNAs and miRNA dysregulation in cancer-associated fibroblasts

Abstract Purpose The present review aimed to assess the role of exosomal miRNAs in cancer-associated fibroblasts (CAFs), normal fibroblasts (NFs), and cancer cells. The roles of exosomal miRNAs and miRNA dysregulation in CAF formation and activation were summarized. Methods All relevant publications...

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Bibliographic Details
Main Authors: Fengming Yang, Zhiqiang Ning, Ling Ma, Weitao Liu, Chuchu Shao, Yongqian Shu, Hua Shen
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Molecular Cancer
Subjects:
Cancer-associated fibroblasts
MiRNA
Exosome
Cancer
Mechanism
Online Access:http://link.springer.com/article/10.1186/s12943-017-0718-4

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