Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Genetic Variation in Neisseria meningitidis Does Not Influence Disease Severity in Meningococcal Meningitis

Neisseria meningitidis causes sepsis and meningitis in humans. It has been suggested that pathogen genetic variation determines variance in disease severity. Here we report results of a genome-wide association study of 486 N. meningitidis genomes from meningococcal meningitis patients and their asso...

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Bibliographic Details
Main Authors: Philip H. C. Kremer, John A. Lees, Bart Ferwerda, Arie van de Ende, Matthijs C. Brouwer, Stephen D. Bentley, Diederik van de Beek
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Medicine
Subjects:
severity
genome-wide association study
genome sequencing
Neisseria meningitidis
thrombocytes
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2020.594769/full

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