The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints

The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints

Constraint-based modeling is a well established modelling methodology used to analyze and study biological networks on both a medium and genome scale. Due to their large size, genome scale models are typically analysed using constraint-based optimization techniques. One widely used method is Flux Ba...

Full description

Bibliographic Details
Main Authors: Olivier Brett G., Bergmann Frank T.
Format: Article
Language:English
Published: De Gruyter 2015-06-01
Series:Journal of Integrative Bioinformatics
Online Access:https://doi.org/10.1515/jib-2015-269
id doaj-cc2e9bc9abbd47df8a645ff4ebd49933
record_format Article
spelling doaj-cc2e9bc9abbd47df8a645ff4ebd499332021-09-06T19:40:32ZengDe GruyterJournal of Integrative Bioinformatics1613-45162015-06-0112266069010.1515/jib-2015-269jib-2015-269The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance ConstraintsOlivier Brett G.0Bergmann Frank T.1Systems Bioinformatics, VU University Amsterdam, Amsterdam, NetherlandsModelling of Biol. Processes, Heidelberg University, Heidelberg, GermanyConstraint-based modeling is a well established modelling methodology used to analyze and study biological networks on both a medium and genome scale. Due to their large size, genome scale models are typically analysed using constraint-based optimization techniques. One widely used method is Flux Balance Analysis (FBA) which, for example, requires a modelling description to include: the definition of a stoichiometric matrix, an objective function and bounds on the values that fluxes can obtain at steady state.https://doi.org/10.1515/jib-2015-269
collection DOAJ
language English
format Article
sources DOAJ
author Olivier Brett G.
Bergmann Frank T.
spellingShingle Olivier Brett G.
Bergmann Frank T.
The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
Journal of Integrative Bioinformatics
author_facet Olivier Brett G.
Bergmann Frank T.
author_sort Olivier Brett G.
title The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
title_short The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
title_full The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
title_fullStr The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
title_full_unstemmed The Systems Biology Markup Language (SBML) Level 3 Package: Flux Balance Constraints
title_sort systems biology markup language (sbml) level 3 package: flux balance constraints
publisher De Gruyter
series Journal of Integrative Bioinformatics
issn 1613-4516
publishDate 2015-06-01
description Constraint-based modeling is a well established modelling methodology used to analyze and study biological networks on both a medium and genome scale. Due to their large size, genome scale models are typically analysed using constraint-based optimization techniques. One widely used method is Flux Balance Analysis (FBA) which, for example, requires a modelling description to include: the definition of a stoichiometric matrix, an objective function and bounds on the values that fluxes can obtain at steady state.
url https://doi.org/10.1515/jib-2015-269
work_keys_str_mv AT olivierbrettg thesystemsbiologymarkuplanguagesbmllevel3packagefluxbalanceconstraints
AT bergmannfrankt thesystemsbiologymarkuplanguagesbmllevel3packagefluxbalanceconstraints
AT olivierbrettg systemsbiologymarkuplanguagesbmllevel3packagefluxbalanceconstraints
AT bergmannfrankt systemsbiologymarkuplanguagesbmllevel3packagefluxbalanceconstraints
_version_ 1717768283891957760

Similar Items